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ea0032p799 | Paediatric endocrinology | ECE2013

Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty

Mouritsen Annette , Frederiksen Hanne , Sorensen Kaspar , Aksglaede Lise , Hagen Casper , Erik Niels , Erik Skakkebaek , M Main Katharina , Andersson Anna-Maria , Juul Anders

Background: Little is known about the possible deleterious effects of phthalate exposure on endogenous sex steroid levels in childrenDesign: A longitudinal study.Materials and methods: 168 Healthy children (84 girls) were examined every 6 months for 5 years, with pubertal staging, measurements of serum levels of DHEAS and Δ4-androstenedione (Adione) and repetitive longitudinal morning urinary measurements of 14 phthalate metab...

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ea0056p977 | Paediatric endocrinology | ECE2018

Association of placental thyroid hormone concentrations with congenital cryptorchidism

Li Zhong-Min , Hernandez-Moreno David , Main Katharina Maria , Skakkebaek Niels Erik , Kiviranta Hannu , Toppari Jorma , Feldt-Rasmussen Ulla , Shen Heqing , Schramm Karl-Werner , De Angelis Meri

The placenta is a highly specialized organ, which ensures nutrient uptake, waste elimination, provides thermo-regulation, prevents passage of some xenobiotic molecules and regulates the quantity of thyroid hormones (TH) necessary for the fetal development. It is known, that even minor changes in maternal TH levels, can alter the fetal growth. Several factors can modify TH levels during pregnancy. Among them, increasing evidences show that prenatal exposure to persistent organi...

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Endocrine Abstracts

Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty

Association of placental thyroid hormone concentrations with congenital cryptorchidism

BiosciAbstracts